No health insurance required
A research study for adults living with chronic, hard to control Gout
A proven gout treatment. Now testing a more convenient schedule.
The FORWARD II study is evaluating an alternative dosing schedule of an IV treatment for chronic gout. Researchers want to learn whether a longer interval between infusions can help maintain control of uric acid levels in adults whose gout has not responded to standard oral medications.

18
Total IV Infusions
Over approx. 12 months
Compensation Provided
For your time & travel
0
Cost to You
No health insurance needed
2 min
Quick Eligibility Check
5 simple questions
Study Eligibility
Who may be a good fit for this study?
This study is for adults whose chronic gout has been difficult to manage even after trying standard oral medications. Below are the key things that may or may not apply to you.
✓ May Qualify
Adults 18 years or older
This study is open to any adult man or woman aged 18 and above.
Gout that has not responded to standard pills
Your gout continues despite trying medications such as those commonly prescribed by a doctor at the highest dose recommended for you, or you cannot take those medications for medical reasons.
Recent gout attacks or visible lumps
You have had 2 or more gout flares in the past year, or you have visible chalky lumps (called tophi) caused by uric acid crystals building up under the skin.
Weight under 352 lbs (160 kg)
The study medication has been tested and dosing is calibrated safely for people within this weight range.
✕ May Not Qualify
Recent serious heart events
People who were hospitalized for heart failure, or treated for a heart attack or serious unstable chest pain in the past 3 months, cannot join for safety reasons.
Long-term strong immune-suppressing medication
People currently taking certain immune-suppressing medications, or high-dose oral steroids over an extended period, are not eligible at this time.
All study-related care is provided at no cost
All gout-related care during the study is fully covered. Health insurance is not required. Compensation for your time and any travel involved in attending visits is also provided.
All study-related visits covered
Compensation for time & travel
No health insurance needed
All lab tests covered
Built on science. Backed by a global sponsor.
This study follows established clinical research guidelines to protect your safety, privacy, and rights at every step.
Sponsored by Horizon Therapeutics
A global biopharmaceutical company sponsoring this study to evaluate a treatment approach for adults living with difficult-to-control gout.
Registered and Regulated
This Phase 4 clinical study is conducted under an approved protocol and follows established clinical research and safety standards.
Reviewed by Independent Ethics Committees
An external review ensures the study is appropriate and that participant rights are protected.
Qualified Research Sites
Conducted at clinical research centers staffed by trained medical professionals experienced in clinical studies.
Voluntary Participation
Taking part is voluntary. You may withdraw at any time without penalty or loss of benefits to which you are otherwise entitled.
Your Privacy Matters
DecenTrialz securely handles your information during the pre-screening process. Your data is kept confidential and managed in accordance with applicable privacy regulations.
Answer 5 questions to see if you could qualify
What to expect, step by step
Here's a clear, plain-language picture of what happens if you decide to get involved:
Online eligibility check
Answer 5 short questions on this page, no forms, no commitment. If your answers suggest you might be eligible, a Decentrialz coordinator will reach out within 3 working days for a no-obligation phone call.
Medical screening & preparation
You'll visit the clinic in Chicago for a thorough health review, blood tests, a physical exam, and an ECG. If all looks good, you'll start a weekly oral medication for 4 weeks to prepare your immune system for the main treatment phase.
Treatment period
You'll receive IV infusions of the study medication at the clinic, roughly every 2 or 4 weeks depending on the group you're assigned to. Each session lasts about 2 hours. You continue the weekly oral medication throughout. During the second half, everyone receives the every-4-week schedule.
Safety follow-up
After your last infusion, the team will check in by phone or email 30 days later. Then, about 3 months after your final dose, you'll come in for one last safety visit at the clinic. After that, you're done!
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Take two minutes, it could change how you manage your gout.
No obligation, no commitment. Just 5 questions to see if this study could be right for you.